SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e043164919e6fdfa38821b7fddc00761e2c155a012b65116491ed2003b435630' 
  AND token = 'mfniq1iotLtOFqtI23/ukLqqmvMCl2v51ZtEnvJc5v8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}