SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '005dcbee7908eede600926a0094ae82da17b5e1a0c7dda9ea7b6156b48c6f879' 
  AND token = 'T3hZSaBlNJAoRYLTLTEtTAtXLO3wEICRH9SheQ4E6yQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}