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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25b71ed95968f0b5ff59c72433a6f238a6339af9c0b6f806abe8cf3f49d81db6' 
  AND token = 'nvi7Dzts0XfZP8/9Jzi+lcPbeW+QSxVQ3KtyyDlGTrI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}