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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '50a25c36c403d5cafe21bfb5d2bd7cab27fc3a45e0e08a0673646abcd7d08651' 
  AND token = '7Z9I8AiwhncfnTNSNUvie2m5OCNySRQ/QuDuRpJOLHs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}