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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2cc7cf02838c38468a2a9e8bccd2165d98172172d46ab42d7c8ab6e83e806941' 
  AND token = 'qaWqG1lf2N6WyRlGSqVAFGG7UHZ2+b6DCeDWYGUIfIw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}