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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd19d5d00a776d8666a676db7d9d274662b126deea6a9da60be6fc75662b5989f' 
  AND token = '6+4QK7TQFqKZ239VfsZqJVQXgbB2JDLbXa1Ijc2nGLM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}