SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5a302bad497461f2a81fd84b3fadac83e0051872117b490a14a35b7ac53a453c' 
  AND token = 'dUwJkm+NnSM7IT+sFvFm/0M1gOLOF1jeuOhwo7panyQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00059

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}