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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9013af9b3d7d5c9dffbfc062fbc55edd5c18cfb389a50b385e62b1d0a0385321' 
  AND token = 'bdFdx6nXaoXMt69bL3AkysaV6+ZW5xg2sdAWgAbJWfc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}