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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '800e66399e74dd001acdd0e26e9a8ad533198ab4cf238028528c0b36a79fc244' 
  AND token = 'EPUw0Qltr+NOBoSdfC3HyI3Be11at22sFAW8aIFWBGI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}