SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c33702690a07257dde1f7658ff826a0672cb9bd9328e6f5c226f6e47a6586e2b' 
  AND token = 'RZ9/2oGXarTw509N8Zqb/uGSbhXK0EKbN1jum5PupJo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}