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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3b462c1e6c22c9b3559aa65de09c3599ace06cb6a8025b81771cec65b7e6468d' 
  AND token = 'FMVFZLAkUPKeIdENaHD7DCseSStk2Rp4NKk/mbV0UOc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}