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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '54d5e52a94db851664d0693162f13070c1cdc7af454d8ec5126fe3f29c4b0e94' 
  AND token = 'MxIFV2rHEHxsAVyz1iRYblyzhRbdvz/LG/17NdLA5hE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}