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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d8e9d132b38848239cfc03e560392a7b86113c5f6eb6ed9125ab557a2d66893' 
  AND token = 'KqFBigMaYRNj0JsboT216L9H0Ap2M+uuu+0zSjf49qc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}