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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd3ec911a9445c441c707060b8eeedb5d0115148e57bf10f7384146d1370ae432' 
  AND token = 'VVPbhru0tWBr8eWODZZe9YgancUPJlTCSamXBkT3epI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}