SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fd414ef09c6839d6376ea2afc2391579bfcba755b5664b88c83009b8f0c99769' 
  AND token = 'matnNm/JupO00xNSb70uOeGAs65+zbohWnlAen9ojNY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}