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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e3c27460f76efc0887baeaf3ce803808da43838e5040582a823296aebe3b1c91' 
  AND token = '0dmzlBT5t6lfnrLgpU1cqugRXeh2m1Y4lCOLXCkBnRo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}