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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '66434178cdd0f1a5b34bc69ca9ae1afcd22f4cc6392bb1c0a61f688f0b5558f2' 
  AND token = 't9WpJp2apnugaMurP7StYHmoQHB6pi05dSJWqmSiY7k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00053

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}