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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2fa6a6f5577d8086ec7a262d2301dac4616683ae321ec5e15e126568b5e0769f' 
  AND token = 'kkCkeFfJuVxKWk5UtF64g9r/6X5v2l1IY7RpAYqZnG0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}