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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e11eb65f692729f528ff06f0b2951f088f9ca6998288f0254e1a8f3dc641ff5f' 
  AND token = 'qVj3bQaJuDbuTPmg2xBa3RNTe9QneSo2hcDqbiSUhbE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}