SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72a1ec13b765b0aae62c01f22dffa9775bcea8d90d74bce86f146c5d474eb9c5' 
  AND token = 'wnZUKQeMiXYmE1b/UOS1W+tOFCtNPnZgL6GuMvZXMBw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}