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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '36b9cabf4a2278f69b7a624b3525c876509a4dbc5870414a352d00434185f857' 
  AND token = 'UYbsk6TTJmjp+nIErxh3/C/zSLPTX4cjrS0EhRHXf44=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}