SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e7465e1b945b102fbbb85f41e914d412294b45ceabd6ea43a948bf92d9f3884' 
  AND token = 'fnyC7mj5dx9/XTl5H67e8exLunyWug69Yqdyim7SERo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}