SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2f09320b9e9f864f7d1544d041190bac6bac9a9af161a561abc84f1c02e5d90e' 
  AND token = 'GwbOsCq+V3HxKPtQya4rQ2GlQAXdH1E63FHaVlvVCzg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}