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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '525dfeed3eec0500d4164fd88620eb2910554fe5aa6426375231a89697f2de4f' 
  AND token = 'x5Ri1wA7n1EoVpvzLBff4a2oPbkpz/0Q2BRzb9gbFDs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}