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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6468ff735f68d38e0985fea6ccc1f2a217d1021f834e8061ee47835050104f5d' 
  AND token = 'Vj7w0tj7sOWnjYbQ58g73Vn7Tan7YziM4RjoEwY1mVE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}