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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e8d61ffe1c827fe8586f1e48bf341b7261b8ce65d56425fa9c76000dfacd52e' 
  AND token = 'bby8jtaQDipUKC2MNCEAK4KrFL5RgIi2spASAd4eDqM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}