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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '12ebd0d29f179cc7182699a8b6e56690aba7432e6e42742ac7222735dad840c2' 
  AND token = '8FbcZjwA0cLS9zCv+2YyYlakEc1TQDgIsvpNo97bYq8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}