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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '768a81e1ab4a1f73e385ddf60b354c6aa4767b05ea212da20884143225348401' 
  AND token = 'ZqOs+MW+stU3Z3wLkb/WXC5kNAXT1YHsZAysj4sry1c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}