SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0ab737a7a802c67f882d4a4264018095c2a17a672e06c3bcac8b87e5b0f9f2d5' 
  AND token = 'fhr0MAc2dMNkmmKkfiO8C3cYs6hSWB2WsAAG+hnaEc4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}