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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e06f82f892de9d9ba2f87bc90e1c0602eb2c3c5ddfed6b7274d153148e0add4' 
  AND token = 'Q+BQCAWA+mRQPjc69oLl9zUD7f/hGgT7tPj6D6nMPQ8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}