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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f4726f7831ce31f52e613e7096aa3d7946bd6ce326c840467868a9fe6c570cb1' 
  AND token = 'xdD799++9K/BcfIq3jDZRnepjDLFnEa04kk43LdMVg4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}