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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f35f9f33015398aea00639e908f3b770bc3448819d8c94b0e944095247c600fa' 
  AND token = 'VOsRs2rDa1f8EuvV1XVnOgrla7sROt3kZ4wj/V71UW4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}