SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7fadb68fabda2871ba81abc18b02b1a1500b696d3acdc018500805e89115ae22' 
  AND token = '+tQHS8tyMWrN6y4LISR+ROvCL8R++7g/RL4y2UQ5Rlc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}