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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0f0dcf338fbac08cf06a0ef4dfcbda2db0074a61051b3ff7965067ab517a4bc4' 
  AND token = 'Rc1nYJdiENtntfpvE/jpvizrDUdi5Bq29dsd8L7tnQI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}