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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c823d4dfcac7e1a784eea65a301eac645095e3539cbcbb50ae14b1778551bb2f' 
  AND token = 'y2IOHctaqIrWRk2RvJe+uyA8U5tLuEyq6L4JPvtSnM4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00064

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}