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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '756d9263c01d6e801aa34ae35b4087c1f70ec8a93fc59d5ee6e1a79bb8e121de' 
  AND token = 'CebN2exMVs1NnD4KxJXv2ZHsg8mElEiFnmt8GK28wFE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}