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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1769008cb1c2d5b72935364e876f0d149790d2d7c8456e886c3a325230767343' 
  AND token = 'H8Beritv5pZivzA5hAh7qU+M4cyS4cLnkAr8PonPy0s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}