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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '810eab6a7505071d84e4435f261f74523ff7ff687cc8f1c8c378067a298a063f' 
  AND token = 'BaExWxoWVI5ptHYfzqWbYY39dfq/b/1NYf+/bc22GO8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}