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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4dbc029eb5ec1bef2501f87964b63eb08eaee5408a2c6eadee93d2e2167716c0' 
  AND token = 'R1K6oOvRkf2auplBmLhD8pKF7LC0qDm+qIS6O/lnCXc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}