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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e18bf2d4fd1fb769a5318079d01d0dc6098c06de970b41e486f1771babbada24' 
  AND token = '+nj2rREVNnUnkVCV4VjgVvsFOuAWXRHJxkeQPeuaXSc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}