SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f00259116903ebe00e48daef1f0da369a666c462023fc1e4199872d9b148b73b' 
  AND token = '7KR22j+AsZAq5bzNb5Kk/YIOHti7m1DJTGXP5mp35qM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}