SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '225c29a325d1f91bfd178c8ebf5d65c05d8c846bd3e03e491483b2dff548780a' 
  AND token = 'ZYBqoxmcVjgNA66ckCYx+N9pLOhSzbepn9+N9T1i7MQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}