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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '925e2f58af2faadf5546570d370b2225f4d0ba40df448f4f4f01717f5f279242' 
  AND token = 'VXJQhhtJJxMduDNOtk8ahMdyfREMivVAC1noPGxgEgA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}