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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f6111137832322cc7145b282f865ef2bf99450febb2e7aecfc9ff86978656f34' 
  AND token = 'Lk8Zq+8baHvqKLnBZbx4P7LsfBtwcUCWFWHC36rKGcQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}