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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e8288007c59c9147327fe61d46d6951e9a17d0928d7b8678fe6e2476f8b7899' 
  AND token = 'Y7n7s/SqH5uEcKCg8JkLiC0wJiGkrD+EZF/5Ls2VFyk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}