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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4dddc62099e822ebe7b92e9b41ab52187f81650445c34b437271593f364dcb02' 
  AND token = 'ttRsnCw4K+awbsPl706o9JAJf3AmCzs1Zx1CnIPuJpY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}