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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2182cddd4b494618eff30446fca3f6f2ec51475267a1ced9bea2a4085d5afce2' 
  AND token = 'TLfp7dmdTKcKcz5C17p1qmZKthfc/ZayTTS0IcV1jfg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}