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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6f2747313040b50e7bbda84dd9c7b0ac91ed5d19e17684402f3142f70cd0f6eb' 
  AND token = 'yVpr6i7s8eBCbhpEUBKu1fVqnEW6KEypseUwCN0CAhM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00078

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}