SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ddd4f75a2882d7215a056caedb4c5f5dcfff0839a41d01ed0d8ffc87efeea26e' 
  AND token = '3li3XN+RMQ9YOt8OPEwNM1WGWmZAHfIkyZXMqzOGi2I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}