SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4cd48f255a958a8aea46f5b587e7f6fb29ac3d345b44b8ce9b160fc2534d9cb7' 
  AND token = 'GbJW+YC8laVIl/2slfQtn7pmEYqWqERdl8i2lHFRNnY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}